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carglumic acid

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Origin: China

Cas No: 1188-38-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    1188-38-1
    Other Names:
    N-CARBAMYL-L-GLUTAMIC ACID
    MF:
    C6H10N2O5, C6H10N2O5
    EINECS No.:
    601-569-3
    Place of Origin:
    Shandong, China
    Type:
    Syntheses Material Intermediates
    Purity:
    99% min
    Brand Name:
    LOOK
    Model Number:
    WJY-1188-38-1
    Application:
    Amino Acids, Amino Acids
    Appearance:
    white powder, White Powder
    Product name:
    N-CARBAMYL-L-GLUTAMIC ACID
    Melting point:
    174°
    Boiling point:
    438.1±45.0 °C
    Density:
    1.499±0.06 g/cm3
    Storage:
    2-8°C
    pka:
    3.71±0.10
    Color:
    White

    Packaging&Delivery

    Packaging Details
    10kg/20kg/drum or as your requirement
    Port
    any port in China
    Lead Time:
    Quantity(Kilograms)1 - 100000>100000
    Est. Time(days)5To be negotiated
  • Property

    CAS No.: 1188-38-1 Formula: C6H10N2O5 Molecular Weight: 190.15400

    Description

    Carglumic acid is an orphan drug, marketed by Orphan Europe under the trade name Carbaglu. Carglumic acid is used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. The initial daily dose ranges from 100 to 250mg/kg, adjusted thereafter to maintain normal plasma levels of ammonia.
    The US FDA approved it for treatment of hyperammonaemia on March 18, 2010. Orphan Drug exclusivity expires on March 18, 2017.

    Basic Info

    Chemical Name carglumic acid
    Synonyms

    (S)-2-Ureidopentanedioic acid;
    N-Carbamyl-L-glutamic acid;
    (2S)-2-(carbamoylamino)pentanedioic acid;

    CAS No. 1188-38-1
    Molecular Formula C6H10N2O5
    Molecular Weight 190.15400
    PSA 129.72000
    LogP 0.06390

    Properties

    Density 1.499g/cm3
    Boiling Point 438.1ºC at 760 mmHg
    Flash Point 218.8ºC
    Refractive Index 1.544
    Storage Condition 2-8ºC
    Vapor Pressure 6.7E-09mmHg at 25°C

    Safety Info

    RTECS LZ9870000
    Safety Statements S26; S36/37
    WGK Germany 3
    Risk Statements R36/37/38
    Hazard Codes Xi
    Signal Word Warning
    Symbol GHS07
    Hazard Declaration H302; H315; H319; H335
    Caution Statement P261; P305 + P351 + P338

    Synthesis Route

    L-glutamic acid+ureacarglumic acid
    potassium cyanate+L-glutamic acidcarglumic acid

    Precursor

    urea
    potassium cyanate
    L-glutamic acid

    Downstream Product

    L-citrulline
    L-glutamic acid

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