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acenocoumarol

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Origin: China

Cas No: 152-72-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 152-72-7 Formula: C19H15NO6 Molecular Weight: 353.32600

    Description

    Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is generic, so is marketed under many brand names worldwide.

    Basic Info

    Chemical Name acenocoumarol
    Synonyms

    Acenocoumarol;

    CAS No. 152-72-7
    Molecular Formula C19H15NO6
    Molecular Weight 353.32600
    PSA 113.33000
    LogP 4.04100

    Properties

    Appearance & Physical State White crystalline solid
    Density 1.427g/cm3
    Boiling Point 546.9ºC at 760mmHg
    Melting Point 196-199ºC
    Flash Point 284.6ºC
    Refractive Index 1.656
    Vapor Pressure 0mmHg at 25°C

    Safety Info

    Hazard Class 6.1(b)
    HS Code 2932209090
    Packing Group III
    RIDADR UN 2811
    Hazard Declaration H302; H315; H319; H335
    Symbol GHS07
    Signal Word Warning
    Caution Statement P261; P305 + P351 + P338

    Synthesis Route

    4-hydroxycoumarin+(Z)-4-(4-Nitrophenyl)-3-buten-2-oneacenocoumarol+acenocoumarol
    4-hydroxycoumarinacenocoumarol
    4-nitrobenzaldehydeacenocoumarol

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 513 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Oral LD50 - Lethal dose, 50 percent kill Rodent - mouse 1470 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - mouse 115 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    4-nitrobenzaldehyde
    4-hydroxycoumarin
    (Z)-4-(4-Nitrophenyl)-3-buten-2-one

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