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(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione

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Origin: China

Cas No: 19457-55-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
19457-55-7
Other Names:
1,2-Dihydro ExeMestane
MF:
C20H26O2
EINECS No.:
19457-55-7
Place of Origin:
Shaanxi, China
Type:
Antibiotic and Antimicrobial Agents
Grade Standard:
Medicine Grade
Brand Name:
Dideu
Model Number:
USP 39
Purity:
99.9%
Test Standard:
EP 9.0/USP39/BP2015
Content:
99.0% to 101.0%
Test method:
HPLC-ESI-MS
Water:
0.5% Max.
Sulfated ash:
0.1% Max.
Heavy metals:
10ppm Max
Total Impurity:
0.5% Max.
Total plate count:
≤1000cfu/g
Yeast and Moulds:
≤100cfu/g
E. Coli.:
Absent
Packaging&Delivery
Packaging Details
25kgs/Drum; 5kgs/Tin&10kgs/Carton
Port
Any main port of China

Property

CAS No.: 19457-55-7 Formula: C20H26O2 Molecular Weight: 298.41900

Description

1,2-Dihydro Exemestane is a related compound of Exemestane.

Basic Info

Chemical Name	(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione
Synonyms	6-methylenandrosta-4-ene-3,17-dione; 6-methyleneandrost-4-ene-3,17-dione; 6-methylen-4-androsten-3,17-dione; Androst-4-ene-3,17-dione,6-methylene-; 6-methylenandrost-4-ene-3; 1,2-Dihydro Exemestane; 6-Methyleneandrost-4-en-3,17-dione; 6-Methyleneandrost-4-ene-3,7-dione; 6-methylene-4-androstene-3,17-dione; 6-methylen-androst-4-ene-3,17-dione;
CAS No.	19457-55-7
Molecular Formula	C20H26O2
Molecular Weight	298.41900
PSA	34.14000
LogP	4.25350

Properties

Density	1.11 g/cm3
Boiling Point	450.8ºC at 760 mmHg
Flash Point	168ºC
Refractive Index	1.555
Vapor Pressure	2.55E-08mmHg at 25°C

Synthesis Route

Formaldehyde+androst-4-ene-3,17-dione→(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione
Diethoxymethane+androst-4-ene-3,17-dione→(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione
Formaldehyde+androst-4-ene-3,17-dione→(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione+(8aR,8bS,10aS,13aS,13bR)-8a,10a-Dimethyl-4,7,8,8a,8b,9,10,10a,12,13,13a,13b-dodecahydro-1H,3H-2-oxa-cyclopenta[a]triphenylene-6,11-dione

Precursor

Formaldehyde
androst-4-ene-3,17-dione
Diethoxymethane
(8R,9S,10R,13S,14S)-3-methoxy-10,13-dimethyl-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one

Downstream Product

exemestane

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