Home > Carbonyl Compounds> 6-[2-[6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl]acetyl]-2,3-dimethoxybenzoic acid

6-[2-[6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl]acetyl]-2,3-dimethoxybenzoic acid

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Origin: China

Cas No: 131-28-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 131-28-2 Formula: C23H27NO8 Molecular Weight: 445.46200

Description

Narceine is an opium alkaloid produced by the Papaver somniferum (opium poppy) plant. It is a bitter, crystalline compound with narcotic effects. It was formerly used as a substitute for morphine.[medical citation needed] Its name is derived from the Greek νάρκη (nárkē), meaning numbness, and the postfix -ine referring to an alkaloid.

Basic Info

Chemical Name	6-[2-[6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl]acetyl]-2,3-dimethoxybenzoic acid
Synonyms	1,6-NAPHTHYRIDINE-2,6(5H)-DICARBOXYLIC ACID,7,8-DIHYDRO-,6-(1,1-DIMETHYLETHYL) ESTER; Benzoic acid, 6-[[6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl]acetyl]-2,3-dimethoxy-; 7,8-DIHYDRO-5H-[1,6]NAPHTHYRIDINE-2,6-DICARBOXYLIC ACID 6-TERT-BUTYL ESTER; 6-BOC-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE-2-CARBOXYLIC ACID; 6-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylic acid; 6-{[6-(2-Dimethylamino-aethyl)-4-methoxy-benzo[1,3]dioxol-5-yl]-acetyl}-2,3-dimethoxy-benzoesaeure; 6-{[6-(2-dimethylamino-ethyl)-4-methoxy-benzo[1,3]dioxol-5-yl]-acetyl}-2,3-dimethoxy-benzoic acid; 6-{[(1,1-dimethylethyl)oxy]carbonyl}-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylic acid;
CAS No.	131-28-2
Molecular Formula	C23H27NO8
Molecular Weight	445.46200
PSA	103.76000
LogP	2.66880

Properties

Density	1.271 g/cm3
Boiling Point	599.3ºC at 760 mmHg
Flash Point	316.3ºC
Refractive Index	1.578
Vapor Pressure	3.26E-15mmHg at 25°C

Synthesis Route

(-)-α-narcotine methiodide→6-[2-[6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl]acetyl]-2,3-dimethoxybenzoic acid
Methyl p-toluenesulfonate+α-Narcotine→6-[2-[6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl]acetyl]-2,3-dimethoxybenzoic acid
dimethyl sulfate→6-[2-[6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl]acetyl]-2,3-dimethoxybenzoic acid

Precursor

dimethyl sulfate
α-Narcotine
(-)-α-narcotine methiodide
Methyl p-toluenesulfonate

Downstream Product

Dimethylamine
3,4-dihydroxybenzoic acid
Ammonia
trimethylamine

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