Home > Carbonyl Compounds> 4-(methylamino)-2-methylsulfanylpyrimidine-5-carbaldehyde

4-(methylamino)-2-methylsulfanylpyrimidine-5-carbaldehyde

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Origin: China

Cas No: 185040-32-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 185040-32-8 Formula: C7H9N3OS Molecular Weight: 183.23100

Description

Intermediate in the preparation of p38 kinase inhibitors

Basic Info

Chemical Name	4-(methylamino)-2-methylsulfanylpyrimidine-5-carbaldehyde
Synonyms	4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxaldehyde; 4-methylamino-2-methylsulfanyl-pyrimidine-5-carbaldehyde; 4-methylamino-2-methylthiopyrimidine-5-carboxaldehyde; 4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxaldehyde;
CAS No.	185040-32-8
Molecular Formula	C7H9N3OS
Molecular Weight	183.23100
PSA	80.18000
LogP	1.12570

Properties

Density	1.278g/cm3
Boiling Point	377.054ºC at 760 mmHg
Flash Point	181.836ºC
Refractive Index	1.588
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2933599090

Synthesis Route

2-Methylthio-4-Chloro-5-Ethoxycarbonylpyrimidine→ethyl 4-(methylamino)-2-methylsulfanylpyrimidine-5-carboxylate+4-(methylamino)-2-methylsulfanylpyrimidine-5-carbaldehyde
[4-(methylamino)-2-methylsulfanylpyrimidin-5-yl]methanol→4-(methylamino)-2-methylsulfanylpyrimidine-5-carbaldehyde
2-Methylthio-4-Chloro-5-Ethoxycarbonylpyrimidine→4-(methylamino)-2-methylsulfanylpyrimidine-5-carbaldehyde

Precursor

2-Methylthio-4-Chloro-5-Ethoxycarbonylpyrimidine
[4-(methylamino)-2-methylsulfanylpyrimidin-5-yl]methanol
ethyl 4-(methylamino)-2-methylsulfanylpyrimidine-5-carboxylate
METHYLAMINE

Downstream Product

6-(2,6-Dichlorophenyl)-8-methyl-2-methylsulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one
8-methyl-2-methylsulfonyl-6-phenylpyrido[2,3-d]pyrimidin-7-one
6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanylpyrido[2,3-d]pyrimidin-7-imine
N-[6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanylpyrido[2,3-d]pyrimidin-7-ylidene]acetamide

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