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4-Iodo-2-methoxynicotinaldehyde

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Origin: China

Cas No: 158669-26-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 158669-26-2 Formula: C7H6INO2 Molecular Weight: 263.03300

Description

This compound is used in the synthesis of insulin-like growth factor 1-receptor inhibitors that display anti-tumor activity.

Basic Info

Chemical Name	4-Iodo-2-methoxynicotinaldehyde
Synonyms	4-iodo-2-methoxypyridine-3-carbaldehyde;
CAS No.	158669-26-2
Molecular Formula	C7H6INO2
Molecular Weight	263.03300
PSA	39.19000
LogP	1.50730

Properties

Density	1.873g/cm3
Boiling Point	328.3ºC at 760mmHg
Flash Point	152.3ºC
Refractive Index	1.642
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2933399090

Synthesis Route

2-Methoxypyridine+N-[2-(dimethylamino)ethyl]-N-methylformamide→4-Iodo-2-methoxynicotinaldehyde
N-ethoxyethyl-N-methylformamide→4-Iodo-2-methoxynicotinaldehyde
Sodium methoxide+2-Fluoro-3-iodopyridine→4-Iodo-2-methoxynicotinaldehyde

Precursor

N-[2-(dimethylamino)ethyl]-N-methylformamide
2-Fluoro-3-iodopyridine
Sodium methoxide
N-ethoxyethyl-N-methylformamide

Downstream Product

2-hydroxy-4-iodo-pyridine-3-carbaldehyde
4-iodo-2-methoxy-pyridine-3-carboxylic acid

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