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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Intermediates> (3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
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(3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol

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Origin: China

Cas No: 641-74-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 641-74-7 Formula: C6H10O4 Molecular Weight: 146.14100

    Basic Info

    Chemical Name (3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
    Synonyms

    3-NITRO-HYDROXYDIPHENYL;
    3,6-Dianhydro-D-mannitol;
    Isomannide;
    (1R,4R,5R,8R)-2,6-dioxabicyclo[3.3.0]octane-4,8-diol;
    Isomaide;
    D-isomannoside;
    1,4:3,6-DIANHYDROMANNITOL;
    (3R,3aR,6R,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol;
    1,4:3,6-Dianhydro-D;
    1,4;
    D-Mannitol, 1,4:3,6-dianhydro-;
    1,4:3,6-dianhydro-D-sorbitol;
    1,4:3,6-dianhydro-D-mannitol;
    D-Isomannide;
    3-Nitro-4-hydroxy diphenyl;

    CAS No. 641-74-7
    Molecular Formula C6H10O4
    Molecular Weight 146.14100
    PSA 58.92000
    LogP -1.49420

    Properties

    Appearance & Physical State Off White Crystals
    Density 1.475 g/cm3
    Boiling Point 372.1ºC at 760 mmHg
    Melting Point 80-85ºC
    Flash Point 178.8ºC
    Refractive Index 1.562
    Stability Decomposition will not occur if used and stored according to specifications.
    Storage Condition Keep container tightly sealed. Store in cool, dry place in tightly closed containers.
    Vapor Pressure 4.71E-07mmHg at 25°C

    Safety Info

    Safety Statements S22-S24/25
    HS Code 2932999099

    Synthesis Route

    D-mannitol→(3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol+1,5-anhydro-D-mannitol
    D-mannitol→(3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol+1,4-anhydrosorbitol
    D-mannitol→(3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol+1,4-anhydrosorbitol

    Precursor

    ethyl acetate
    1,4:3,6-dianhydro-2,5-di-O-benzoyl-D-mannitol
    2-Methoxypropene
    D-mannitol

    Downstream Product

    (6-methylsulfonyloxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl) methanesulfonate
    (3aS,6aS)-3a,6a-dihydrofuro[5,4-d]furan-3,6-dione
    (3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
    Isosorbide

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