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3-Hydroxy-2,2-Dimethylpropanal

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Origin: China

Cas No: 597-31-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 597-31-9 Formula: C5H10O2 Molecular Weight: 102.13200

Description

3-Hydroxy-2,2-dimethylpropanal is used to prepare 4,1-benzoxazepines as squalene synthase inhibitors and their inhibition of cholesterol synthesis. It is also used to prepare chiral cyanohydrins.

Basic Info

Chemical Name	3-Hydroxy-2,2-Dimethylpropanal
Synonyms	3-Hydroxy-2,2-dimethylpropanal; Hydroxypivalaldehyde;
CAS No.	597-31-9
Molecular Formula	C5H10O2
Molecular Weight	102.13200
PSA	37.30000
LogP	0.20380

Properties

Density	0.964g/cm3
Boiling Point	204.4ºC at 760mmHg
Flash Point	60.3ºC
Refractive Index	1.421

Safety Info

HS Code	2912491000

Synthesis Route

Formaldehyde+isobutyraldehyde→3-Hydroxy-2,2-Dimethylpropanal
Formaldehyde+isobutyraldehyde→3-Hydroxy-2,2-Dimethylpropanal+NEOPENTYL GLYCOL MONO(HYDROXYPIVALATE)
Formaldehyde+2-methyl-1-trimethylsilyloxy-1-propene→3-Hydroxy-2,2-Dimethylpropanal

Precursor

2-methyl-1-trimethylsilyloxy-1-propene
5,5-dimethyl-2-(1',1'-dimethyl-2'-hydroxyethyl)-4-hydroxy-1,3-dioxane
Formaldehyde
isobutyraldehyde

Downstream Product

1-(piperidin-1-ylmethyl)naphthalen-2-ol
1-(2,3-dihydro-2,2-dimethyl-1H-naphtho[2,1-b]pyran-3-yl)piperidine
2,2-dimethylpentane-1,3-diol
2,2-dimethyl-3-oxopropanenitrile

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