Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (2R,3R,4S,5R,6R)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-6-methylsulfanyloxane-3,4,5-triol

(2R,3R,4S,5R,6R)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-6-methylsulfanyloxane-3,4,5-triol

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Origin: China

Cas No: 14810-93-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 14810-93-6 Formula: C9H19NO5S Molecular Weight: 253.31600

Description

Intermediate in the production of biosynthetic antibiotics

Basic Info

Chemical Name	(2R,3R,4S,5R,6R)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-6-methylsulfanyloxane-3,4,5-triol
Synonyms	methyl thiolincosaminide; Methyl \|A-Thiolincosaminide; Methyl 1-thiolincosaminide; Methyl 6-Amino-6,8-dideoxy-1-thio-D-erythro-\|A-D-galacto-octopyranoside;
CAS No.	14810-93-6
Molecular Formula	C9H19NO5S
Molecular Weight	253.31600
PSA	141.47000
LogP	-1.43460

Synthesis Route

lincomycin→(trans)-4-Propyl-1-methyl-L-proline+(2R,3R,4S,5R,6R)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-6-methylsulfanyloxane-3,4,5-triol
Methyl 6-Acetamido-6,8-dideoxy-1-thio-D-erythro-α-D-galacto-octopyranoside→(2R,3R,4S,5R,6R)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-6-methylsulfanyloxane-3,4,5-triol
methyl (E)-2,3-di-O-benzyl-6,7,8-trideoxy-α-D-galacto-oct-6-enopyranoside→(2R,3R,4S,5R,6R)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-6-methylsulfanyloxane-3,4,5-triol

Precursor

Methyl 2,3-Bis-O-(phenylmethyl)-6,8-dideoxy-7,6-(2-(N,N-dimethylamino)-1-oxa-3-azaprop-2-eno)-D-erythro-α-D-galacto-octopyranoside
methyl 6,7-anhydro-2,3-di-O-benzyl-8-deoxy-α-D-threo-D-galacto-octopyranoside
methyl (E)-4-O-benzoyl-2,3-di-O-benzyl-6,7,8-trideoxy-α-D-galacto-oct-6-enoside
Methyl 6-Acetamido-6,8-dideoxy-1-thio-D-erythro-α-D-galacto-octopyranoside

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