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(2R,3aR,6aR)-Ramipril

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Origin: China

Cas No: 129939-63-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 129939-63-5 Formula: C23H32N2O5 Molecular Weight: 416.51100

Description

An isomer of the angiotensin-converting enzyme (ACE) inhibitor Ramipril. Ramipril impurity N.

Basic Info

Chemical Name	(2R,3aR,6aR)-Ramipril
Synonyms	(2R,3aR,6aR)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]a mino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (n on-preferred name);
CAS No.	129939-63-5
Molecular Formula	C23H32N2O5
Molecular Weight	416.51100
PSA	95.94000
LogP	2.71200

Synthesis Route

(E)-(-)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid hydrochloride+N-[1-(S)-Ethoxycarbonyl-3-phenylpropyl]-L-alanine-N-carboxyanhydride→(2R,3aR,6aR)-Ramipril+Ramipril

Precursor

(E)-(-)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid hydrochloride
N-[1-(S)-Ethoxycarbonyl-3-phenylpropyl]-L-alanine-N-carboxyanhydride

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