Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane

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Origin: China

Cas No: 119302-24-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
119302-24-8
Other Names:
Rocuronium bromide EP Impurity A
MF:
C29H48N2O4, C29H48N2O4
EINECS No.:
NA
Place of Origin:
Shandong China, Shandong China
Type:
Pharmaceutical Intermediates
Purity:
99%, 99%
Brand Name:
Fousi, Fousi
Model Number:
FS119302-24-8
Application:
Chemical reagent
Appearance:
White Powder, White Powder
Product name:
Rocuronium bromide EP Impurity A
Form:
Powder
CAS:
119302-24-8
EINECS:
NA
Color:
White
Packaging&Delivery
Packaging Details
1kg/drum,5kg/drum, 10kg/drum,25kg/drum,200kg/drum
Port
QINGDAO ,SHANGHAI
Lead Time:
Quantity(Milligrams) 1 - 1 >1
Est. Time(days) 7 To be negotiated

Property

CAS No.: 119302-24-8 Formula: C29H48N2O4 Molecular Weight: 488.70200

Description

This compound is used in the synthesis of the neuromuscular blocking agent rocuronium bromide.

Basic Info

Chemical Name	(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
Synonyms	RocuroniuM BroMide InterMediate VIII;
CAS No.	119302-24-8
Molecular Formula	C29H48N2O4
Molecular Weight	488.70200
PSA	62.24000
LogP	3.58250

Properties

Density	1.17
Boiling Point	574.1ºC at 760 mmHg
Flash Point	301ºC
Refractive Index	1.573
Vapor Pressure	1.44E-15mmHg at 25°C

Safety Info

HS Code	2942000000

Synthesis Route

(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol+Acetic anhydride→(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane+(2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3,17-bis(acetyloxyoxy)androstane
(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol+Acetic anhydride→(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane+(2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3,17-bis(acetyloxyoxy)androstane
N-acetylimidazole+(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol→(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane

Precursor

acetyl chloride
Acetic anhydride
N-acetylimidazole
(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol

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