CAS No.: 2140-46-7 Formula: C27H46O2 Molecular Weight: 402.65300
An oxygenated derivative of Cholesterol; an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.
Chemical Name | 25-hydroxycholesterol |
Synonyms | 25-Hydroxy Cholesterol; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; |
CAS No. | 2140-46-7 |
Molecular Formula | C27H46O2 |
Molecular Weight | 402.65300 |
PSA | 40.46000 |
LogP | 6.50360 |
Density | 1.03g/cm3 |
Boiling Point | 513.1ºC at 760mmHg |
Flash Point | 213.5ºC |
Refractive Index | 1.538 |
Vapor Pressure | 1.13E-12mmHg at 25°C |
Safety Statements | S26; S36; S45 |
Risk Statements | R20/21/22; R36/37/38; R48 |
Hazard Codes | Xn |
Caution Statement | P261; P280; P305 + P351 + P338 |
Hazard Declaration | H302; H312; H315; H319; H332; H335; H373 |
Signal Word | Warning |
Symbol | GHS07, GHS08 |
[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate→25-hydroxycholesterol
24(S),25-epoxycholesterol→25-hydroxycholesterol+(24S)-24-hydroxycholesterol
cholest-5-ene-3β,25-diol 3-tetrahydropyran-2-yl ether→25-hydroxycholesterol
3β-(tert-butyldimethylsiloxy)cholest-5-en-25-ol
[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
24(S),25-epoxycholesterol
6β-Methoxy-25-<(tetrahydropyran-2yl)oxy>-3β,5-cyclo-5α-cholestan
[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-fluoro-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol