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2’,3’-Isopropylidene Adenosine-5’-carboxylic Acid

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Origin: China

Cas No: 19234-66-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 19234-66-3 Formula: C13H15N5O5 Molecular Weight: 321.28900

Description

Used in the preparation of nucleosides as adenosine A3 receptor agonists.

Basic Info

Chemical Name	2’,3’-Isopropylidene Adenosine-5’-carboxylic Acid
Synonyms	4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxylic acid;
CAS No.	19234-66-3
Molecular Formula	C13H15N5O5
Molecular Weight	321.28900
PSA	134.61000
LogP	0.49180

Properties

Density	1.92 g/cm3
Boiling Point	628.9ºC at 760 mmHg
Flash Point	334.1ºC
Refractive Index	1.828
Vapor Pressure	1.11E-16mmHg at 25°C

Synthesis Route

2',3'-O-Isopropylideneadenosine→2’,3’-Isopropylidene Adenosine-5’-carboxylic Acid
adenosine→2’,3’-Isopropylidene Adenosine-5’-carboxylic Acid
4-nitrophenyl (3aS,4S,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylate→2’,3’-Isopropylidene Adenosine-5’-carboxylic Acid

Precursor

2',3'-O-Isopropylideneadenosine
adenosine
4-nitrophenyl (3aS,4S,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylate

Downstream Product

5'-(N-CYCLOPROPYL)CARBOXAMIDOADENOSINE
5-(6-aminopurin-9-yl)-N,3,4-trihydroxyoxolane-2-carboxamide
9-riburonosyladenine
Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-, monohydrate, .β.-D-

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