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2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline

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Origin: China

Cas No: 60547-97-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
60547-97-9
Other Names:
60547-97-9
MF:
C14H19N5O2
EINECS No.:
N/A
Place of Origin:
China
Type:
Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
99.0%min
Brand Name:
Sartort
Model Number:
APIs & Intermediates
Application:
Fine Chemical Intermediate
Appearance:
N/A
Packaging&Delivery
Packaging Details
25kg
Port
Any port in China
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 3 To be negotiated

Property

CAS No.: 60547-97-9 Formula: C14H19N5O2 Molecular Weight: 289.33300

Description

Metabolite of Prazosin. It is also an impurity arising in the synthesis of Terazosin.

Basic Info

Chemical Name	2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline
Synonyms	6,7-dimethoxy-2-piperazin-1-ylquinazolin-4-amine;
CAS No.	60547-97-9
Molecular Formula	C14H19N5O2
Molecular Weight	289.33300
PSA	85.53000
LogP	1.61380

Properties

Appearance & Physical State	White powder
Density	1.265 g/cm3
Boiling Point	527ºC at 760 mmHg
Melting Point	219-221ºC (dec.)
Flash Point	272.5ºC
Refractive Index	1.63
Storage Condition	Refrigerator

Safety Info

HS Code	2933499090
Hazard Codes	Xi

Synthesis Route

4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-piperazine-1-carboxylic acid benzyl ester→2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline
piperazine+2-Chloro-4-amino-6,7-dimethoxyquinazoline→2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline
2-Chloro-4-amino-6,7-dimethoxyquinazoline→2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline

Precursor

2-Chloro-4-amino-6,7-dimethoxyquinazoline
4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-piperazine-1-carboxylic acid benzyl ester
piperazine

Downstream Product

prazosin hydrochloride
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(3-bicyclo[2.2.2]octa-2,5-dienyl)methanone
4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-N-phenylpiperazine-1-carbothioamide
doxazosin

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