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2-naphthaldehyde

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Origin: China

Cas No: 66-99-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 66-99-9 Formula: C11H8O Molecular Weight: 156.18100

Description

2-Naphthalenecarboxaldehyde is used to prepare chalcone analogs with increased antileishmanial activities. It is also used to synthesize (aryl)(oxo)spiro[cyclopropane-1,3'-indole] derivatives with their activities as HIV-1 non-nucleoside reverse transcriptase inhibitors.

Basic Info

Chemical Name	2-naphthaldehyde
Synonyms	naphthalene-2-carbaldehyde; 2-Naphthaldehyde; 2-Naphthalenecarboxaldehyde;
CAS No.	66-99-9
Molecular Formula	C11H8O
Molecular Weight	156.18100
PSA	17.07000
LogP	2.65230

Properties

Appearance & Physical State	white to off white crystals
Density	1.155 g/cm3
Boiling Point	160ºC (19 torr)
Melting Point	58-62ºC
Freezing Point	1.0755
Flash Point	179.5ºC
Refractive Index	1.6211 (99ºC)
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info

RTECS	QJ0190010
Safety Statements	S24/25
HS Code	29122900
WGK Germany	3
Packing Group	I; II; III
Risk Statements	R36/37/38
Hazard Codes	Xn; Xi

Synthesis Route

2-Methylnaphthalene→4-Methylphthalic Acid+trimellitic acid
2-Methylnaphthalene→(2-naphthyl)methanol+6-methylnaphthalene-1,4-dione
(2-naphthyl)(1,2,3,4,5-pentamethyl-2,4-cyclopentadienyl)methanol→1,2,3,4,5-Pentamethylcyclopentadiene+2-naphthaldehyde

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	Supelcowax-10	-	2407.	temperature ramp
Capillary	Methyl Silicone	-	1468.	custom temperature program
Capillary	SPB-5	-	258.2	temperature ramp
Capillary	DB-5	-	259.1	custom temperature program
Capillary	DB-5MS	-	257.9	custom temperature program

Precursor

(2-naphthyl)methanol
2-naphthalen-2-yl-1,3-dithiane
naphthalene-2-carbonyl chloride
2-Naphthoic Acid

Downstream Product

diethoxyphosphoryl(naphthalen-2-yl)methanol
2-Methyl-1,2'-dinaphthyl Ketone
5-(naphthalen-2-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-naphthalen-2-ylpropanoic acid

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