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2-methyl-4-nitro-5-propylpyrazole-3-carboxamide

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Origin: China

Cas No: 139756-01-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 139756-01-7 Formula: C8H12N4O3 Molecular Weight: 212.20600

Description

Intermediate in the production of Sildenafil.

Basic Info

Chemical Name	2-methyl-4-nitro-5-propylpyrazole-3-carboxamide
Synonyms	1H-Pyrazole-5-carboxamide,1-methyl-4-nitro-3-propyl; 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide; 1-methyl-4-nitro-3-propyl-1H-5-pyrazole carboxamide; 1-methyl4-nitro-3-n-propylpyrazole-5-carboxamide; 1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide; 2-methyl-4-nitro-5-propyl-2H-pyrazole-3-carboxamide;
CAS No.	139756-01-7
Molecular Formula	C8H12N4O3
Molecular Weight	212.20600
PSA	106.73000
LogP	1.60320

Properties

Density	1.453 g/cm3
Boiling Point	334.559ºC at 760 mmHg
Flash Point	156.136ºC
Refractive Index	1.629
Vapor Pressure	0.000127mmHg at 25°C

Safety Info

HS Code	2933199090

Synthesis Route

2-methyl-4-nitro-5-propylpyrazole-3-carboxylic acid→2-methyl-4-nitro-5-propylpyrazole-3-carboxamide
1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid→2-methyl-4-nitro-5-propylpyrazole-3-carboxamide
Ethyl 2,4-dioxoheptanoate→2-methyl-4-nitro-5-propylpyrazole-3-carboxamide

Precursor

2-methyl-4-nitro-5-propylpyrazole-3-carboxylic acid
1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid
Ethyl 2,4-dioxoheptanoate
ethyl 2-methyl-5-propylpyrazole-3-carboxylate

Downstream Product

4-[[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylbenzoyl]amino]-2-methyl-5-propylpyrazole-3-carboxamide
5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide
4-[(2-ethoxybenzoyl)amino]-2-methyl-5-propylpyrazole-3-carboxamide

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