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2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide

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Origin: China

Cas No: 302964-24-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
302964-24-5
Other Names:
2-phenylethyl bromide
MF:
C11H10ClN3OS, C11H10ClN3OS
EINECS No.:
1806241-263-5
Place of Origin:
Shandong China, Shandong China
Type:
Pharmaceutical Intermediates
Purity:
99%, 99%
Brand Name:
SINCERE-CHEM
Model Number:
SINCERE-CHEM-302964-24-5
Application:
Pharmaceutical Intermediates, Pharmaceutical Intermediates
Appearance:
White powder, White powder
Product name:
2-phenylethyl bromide
CAS No:
302964-24-5
COA:
Availale
MW:
267.73
Density:
1.474±0.06 g/cm3(Predicted)
Packaging&Delivery
Packaging Details
Foil bag or 25kg/ Fiber drum
Port
Shanghai Port, China
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 3 To be negotiated

Property

CAS No.: 302964-24-5 Formula: C11H10ClN3OS Molecular Weight: 267.73500

Description

2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide, is a precursor in the synthesis of Dasatinib, a protein tyrosine kinase inhibitor, and also for 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives, used as potent and selective anti-tumor drugs.

Basic Info

Chemical Name	2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide
Synonyms	2-amino-N-(2-cliloro-6-metliylplienyl)thiazole-5-carboxamide; N-(2-chloro-6-methylphenyl)-2-amino-5-thiazolecarboxamide; 2-aminothiazole-5-carboxylic acid (2-chloro-6-methylphenyl)amide; 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide; 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide;
CAS No.	302964-24-5
Molecular Formula	C11H10ClN3OS
Molecular Weight	267.73500
PSA	96.25000
LogP	3.59360

Properties

Density	1.474 g/cm3
Boiling Point	362ºC at 760 mmHg
Flash Point	172.7ºC
Refractive Index	1.714

Safety Info

HS Code	2934100090

Synthesis Route

(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide+thiourea→2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide
thiourea→2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide
tert-butyl {5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}carbamate→2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide

Precursor

(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide
thiourea
tert-butyl {5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl}carbamate

Downstream Product

Dasatinib
N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide

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