Home > Organofluorine Compounds> 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine

2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine

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Origin: China

Cas No: 1513-69-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1513-69-5 Formula: C5H4F3N3O Molecular Weight: 179.10000

Basic Info

Chemical Name	2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
Synonyms	2-amino-6-(trifluoromethyl)-1H-pyrimidin-4-one; 2-AMINO-4-HYDROXY-6-(TRIFLUOROMETHYL)PYRIMIDINE;
CAS No.	1513-69-5
Molecular Formula	C5H4F3N3O
Molecular Weight	179.10000
PSA	72.03000
LogP	1.36440

Properties

Density	1.75g/cm3
Boiling Point	187ºC at 760 mmHg
Melting Point	289.5-293.5ºC(lit.)

Safety Info

Safety Statements	S26
HS Code	2933599090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Symbol	GHS07
Signal Word	Warning
Hazard Declaration	H315; H319; H335
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

Guanidine nitrate+Ethyl 4,4,4-trifluoroacetoacetate→2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
Methyl 4,4,4-Trifluoroacetoacetate+Guanidine hydrochloride→2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
Guanidine hydrochloride+Ethyl 4,4,4-trifluoroacetoacetate→2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine

Precursor

Guanidine nitrate
Ethyl 4,4,4-trifluoroacetoacetate
Guanidine hydrochloride
Methyl 4,4,4-Trifluoroacetoacetate

Downstream Product

4-methoxy-6-(trifluoromethyl)pyrimidin-2-amine
2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine

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