Home > Organofluorine Compounds> 2,4-Dichloro-6-(Trifluoromethyl)Pyrimidine

2,4-Dichloro-6-(Trifluoromethyl)Pyrimidine

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Origin: China

Cas No: 16097-64-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 16097-64-6 Formula: C5HCl2F3N2 Molecular Weight: 216.97600

Description

2,4-Dichloro-6-trifluoromethylpyrimidine is a useful synthetic intermediate. It can be used to synthesize 2,4-diaminopyrimidines derivatives that show antiplasmodial activities.

Basic Info

Chemical Name	2,4-Dichloro-6-(Trifluoromethyl)Pyrimidine
Synonyms	2,4-Dichloro-6-(trifluoromethyl)pyrimidine;
CAS No.	16097-64-6
Molecular Formula	C5HCl2F3N2
Molecular Weight	216.97600
PSA	25.78000
LogP	2.80220

Properties

Density	1.627g/cm3
Boiling Point	206.9ºC at 760mmHg
Flash Point	78.9ºC
Refractive Index	1.47
Vapor Pressure	0.334mmHg at 25°C

Safety Info

HS Code	2933599090

Synthesis Route

6-(Trifluoromethyl)uracil→2,4-Dichloro-6-(Trifluoromethyl)Pyrimidine
4-Chloro-6-trifluoromethylpyrimidin-2-yldichlorophosphate→2,4-Dichloro-6-(Trifluoromethyl)Pyrimidine
4-Amino-6-trifluoromethylpyrimidin-2-ol Hydrochloride→2,4-Dichloro-6-(Trifluoromethyl)Pyrimidine

Precursor

4-Amino-6-trifluoromethylpyrimidin-2-ol Hydrochloride
4-Chloro-6-trifluoromethylpyrimidin-2-yldichlorophosphate
6-(Trifluoromethyl)uracil
4-Chloro-2-(Methylsulfanyl)-6-(Trifluoromethyl)Pyrimidine

Downstream Product

2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine
2-Chloro-6-(trifluoromethyl)pyrimidin-4-amine

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