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(1S,3R,4S,5S)-4,6,6-trimethylbicyclo[3.1.1]heptane-3,4-diol

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Origin: China

Cas No: 18680-27-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
18680-27-8
Other Names:
18680-27-8
MF:
C10H18O2
EINECS No.:
18680-27-8
Place of Origin:
Shandong, China
Type:
Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
≥99%
Brand Name:
Finerchem
Model Number:
18680-27-8
Application:
Bortezomib intermediate
Appearance:
White powder
Molecular Weight:
170.25
Assay:
≥99%
Product name:
(1S,2S,3R,5S)-(+)-2,3-Pinanediol
Melting point:
53-57
Packaging&Delivery
Packaging Details
Aluminum foil bag for within 10kg
Fiber drum for 10kg and more
Port
SHANGHAI, BEIJING, QINGDAO, SHENZHEN
Lead Time:
Quantity(Kilograms) 1 - 10 >10
Est. Time(days) 2 To be negotiated

Property

CAS No.: 18680-27-8 Formula: C10H18O2 Molecular Weight: 170.24900

Description

(1S,2S,3R,5S)-(+)-2,3-Pinanediol is a bicyclic monoterpene diols that has been shown to induce differentiation of S91 melanoma and PC12 pheochromocytoma cells and thus provide possible therapeutic and sunless tanning use. It is also used in the transformation of isopinocampheol and caryophyllene oxide.

Basic Info

Chemical Name	(1S,3R,4S,5S)-4,6,6-trimethylbicyclo[3.1.1]heptane-3,4-diol
Synonyms	(1S,2S,3R,5S)-(+)-2,3-Pinanediol; (1S,2S,3R,5S)-(+)-Pinanediol; Pinanediol,(+); (1S,2S,3R\|,5S)-(+)-Pinanediol; UNII-Y6ZCV4AVRA; (+)-2-Hydroxyisopinocampheol; (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol; 2alpha,3alpha-Pinanediol;
CAS No.	18680-27-8
Molecular Formula	C10H18O2
Molecular Weight	170.24900
PSA	40.46000
LogP	1.16430

Properties

Appearance & Physical State	white to light beige crystalline powder, crystals
Density	1.091 g/cm3
Boiling Point	263.738ºC at 760 mmHg
Melting Point	53-57ºC
Flash Point	>230°F
Refractive Index	1.52
Storage Condition	2-8ºC
Vapor Pressure	0.001mmHg at 25°C

Safety Info

Safety Statements	S24/25
HS Code	2906199090

Synthesis Route

(+)-α-Pinene→(1S,3R,4S,5S)-4,6,6-trimethylbicyclo[3.1.1]heptane-3,4-diol
(1S,4S,5S)-4-hydroxy-4,6,6-trimethylbicyclo[3.1.1]heptan-3-one→(1S,3R,4S,5S)-4,6,6-trimethylbicyclo[3.1.1]heptane-3,4-diol
(+)-α-Pinene→(1S,3R,4S,5S)-4,6,6-trimethylbicyclo[3.1.1]heptane-3,4-diol+(1S,4S,5S)-4-hydroxy-4,6,6-trimethylbicyclo[3.1.1]heptan-3-one

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	HP-5MS	-	1313.	temperature ramp
Capillary	DB-5	-	1319.	temperature ramp
Capillary	Supelcowax-10	-	2197.	temperature ramp

Precursor

(1S,4S,5S)-4-hydroxy-4,6,6-trimethylbicyclo[3.1.1]heptan-3-one
(+)-α-Pinene
(3R)-3-(benzyloxy)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane
(1RS:2RS)-2-acetoxy-pinanone-3

Downstream Product

boron,4,6,6-trimethylbicyclo[3.1.1]heptane-4,5-diol
(2R,3R)-Diisopropyl 2,3-dihydroxysuccinate
(3aS,4S,6S,7aR)-3a,5,5-trimethyl-2-phenylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole
(3aS,4S,6S,7aR)-2-Isobutyl-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole

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