Home > Alcohols> (1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

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Origin: China

Cas No: 327611-65-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 327611-65-4 Formula: C11H21NO Molecular Weight: 183.29100

Basic Info

Chemical Name	(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL
Synonyms	Valiolamine; acetylcyclopropyl docetaxel; Valiolamine hydrate; Valinolamine; acetocyclopropyl taxotere;
CAS No.	327611-65-4
Molecular Formula	C11H21NO
Molecular Weight	183.29100
PSA	46.25000
LogP	2.07860

Properties

Density	0.973g/cm3
Boiling Point	257.5ºC at 760 mmHg
Flash Point	109.6ºC
Refractive Index	1.486

Synthesis Route

ethyl (1S,2S,3R,5S)-2-amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylate→(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL
(1S,2S,5R,7S)-2,8,8-trimethyl-3-azatricyclo[5.1.1.02,5]nonan-4-one→(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL
(+)-α-Pinene→(1S,2S,3R,5S)-(2-AMINO-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPT-3-YL)-METHANOL

Precursor

(+)-α-Pinene
(1S,2S,5R,7S)-2,8,8-trimethyl-3-azatricyclo[5.1.1.02,5]nonan-4-one
ethyl (1S,2S,3R,5S)-2-amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylate

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