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16β-methyl-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione

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Origin: China

Cas No: 1879-77-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 1879-77-2 Formula: C22H29FO4 Molecular Weight: 376.46200

Basic Info

Chemical Name	16β-methyl-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione
Synonyms	1,4-PREGNADIEN-9ALPHA-FLUORO-16ALPHA-METHYL-11BETA,17,DIOL-3,20-DIONE; DOXIBETASOL;
CAS No.	1879-77-2
Molecular Formula	C22H29FO4
Molecular Weight	376.46200
PSA	74.60000
LogP	2.92330

Properties

Melting Point	230 - 234 °C
Vapor Pressure	2.59E-13mmHg at 25°C

Synthesis Route

16β-methyl-9β,11β-epoxy-17α-hydroxy-1,4-pregnadiene-3,20-dione→16β-methyl-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione
16β-methyl-17α-hydroxy-pregna-1,4,9(11)-triene-3,20-dione→16β-methyl-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione
3β-acetoxy-16α,17α-epoxy-5α-pregn-9(11)-en-20-one→16β-methyl-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione

Precursor

3β-acetoxy-16α,17α-epoxy-5α-pregn-9(11)-en-20-one
16β-methyl-9β,11β-epoxy-17α-hydroxy-1,4-pregnadiene-3,20-dione
16β-methyl-17α-hydroxy-pregna-1,4,9(11)-triene-3,20-dione

Downstream Product

betamethasone
betamethasone acetate

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