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Picture of 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene

1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene

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Origin: China

Cas No: 53-19-0

Specification: 99%min

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 53-19-0 Formula: C14H10Cl4 Molecular Weight: 320.04100

    Description

    An Antineoplastic. Used as an adrenolytic agent.

    Basic Info

    Chemical Name 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
    Synonyms

    2,4'-Ddd;
    Mitotane;
    Lysodren;
    (2,4'-Dichlorodiphenyl)dichloroethane;
    Chlodithane;
    Mitotane (Lsodren);
    Mitotan;
    o,p'-DDD;
    Khlodithan;
    Chloditan;
    Chlodithan;

    CAS No. 53-19-0
    Molecular Formula C14H10Cl4
    Molecular Weight 320.04100
    PSA 0.00000
    LogP 5.92900

    Properties

    Appearance & Physical State Crystalline Solid
    Density 1.372 g/cm3
    Boiling Point 398.9ºC at 760 mmHg
    Melting Point 76-78ºC
    Flash Point 194.2ºC
    Storage Condition APPROX 4ºC

    Safety Info

    RTECS KH7880000
    Hazard Class 6.1(b)
    Safety Statements S36/37
    HS Code 2903999090
    Packing Group III
    WGK Germany 3
    RIDADR UN 3249
    Risk Statements R40
    Hazard Codes Xn

    Synthesis Route

    O,P'-DDT1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene+1-chloro-4-(1-phenylethyl)benzene
    2,2-dichloro-1-(2-chlorophenyl)ethanol+chlorobenzene1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
    chlorobenzene1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral TDLo - Lowest published toxic dose Human - man 17 gm/kg/35W 1.Behavioral-somnolence (general depressed activity)
    Oral TDLo - Lowest published toxic dose Human - woman 800 mg/kg/4D 1.Skin and Appendages-dermatitis, other (after systemic exposure)
    Oral TDLo - Lowest published toxic dose Human - woman 11 gm/kg/15W 1.Vascular-BP lowering not characterized in autonomic section
    2.Blood-normocytic anemia
    3.Blood-pigmented or nucleated red blood cells

    Precursor

    O,P'-DDT
    2,2-dichloro-1-(2-chlorophenyl)ethanol
    DDT
    chlorobenzene

    Downstream Product

    1-chloro-2-[1,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
    1-chloro-2-[1-(4-chlorophenyl)ethenyl]benzene
    2,4-Dichlorobenzophenone
    1-chloro-2-[1-(4-chlorophenyl)ethyl]benzene

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