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(+)-usnic acid

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начало: Китай

Кас Но: 7562-61-0

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 100 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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CAS No.: 7562-61-0 Formula: C18H16O7 Molecular Weight: 344.31500

Description

Usnic acid is a naturally occurring dibenzofuran derivative found in several lichen species with the formula C18H16O7. It was first isolated by German scientist W. Knop in 1844 and first synthesized between 1933-1937 by Curd and Robertson. Usnic acid was identified in many genera of lichens including Usnea, Cladonia, Hypotrachyna, Lecanora, Ramalina, Evernia, Parmelia and Alectoria. Although it is generally believed that usnic acid is exclusively restricted to lichens, in a few unconfirmed isolated cases the compound was found in kombucha tea and non-lichenized ascomycetes.
At normal conditions, usnic acid is a bitter, yellow, solid substance. It is known to occur in nature in both the d- and l-forms as well as a racemic mixture. Salts of usnic acid are called usnates (e.g. copper usnate).

Basic Info

Chemical Name	(+)-usnic acid
Synonyms	(9BR)-2,6-diacetyl-1,7,9-trihydroxy-8,9b-dimethyldibenzo[b,d]furan-3(9bH)-one; 1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-, (9bR)-; (+)-Usniacin;
CAS No.	7562-61-0
Molecular Formula	C18H16O7
Molecular Weight	344.31500
PSA	121.13000
LogP	2.12660

Properties

Density	1.54 g/cm3
Boiling Point	605.4ºC at 760 mmHg
Melting Point	201-203ºC(lit.)
Flash Point	223.3ºC
Storage Condition	2-8ºC

Safety Info

RTECS	HP5295050
Safety Statements	S36
HS Code	2917399090
WGK Germany	3
Risk Statements	R22
Hazard Codes	Xn

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	838 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Oral	TDLo - Lowest published toxic dose	Rodent - mouse	1500 ug/kg,female 1 day(s) after conception	1.Reproductive-Fertility-female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

Downstream Product

(S)-5,7-diacetoxy-8-acetyl-3,4a,6-trimethyl-4aH-benzo[4',5']furo[2',3':4,5]benzo[1,2-d]isoxazol-4-one

(S)-3-acetyl-4-hydroxy-5,8,10a-trimethyl-7H,10aH-2,6-dioxa-7-aza-9,1-epiethanylylidene-cycloocta[cd]indene-10,11-dione

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