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Vitamin D2

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Origin: China

Cas No: 50-14-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
50-14-6
Other Names:
vitamin D2
MF:
C28H44O
EINECS No.:
200-014-9
Place of Origin:
China
Type:
Vitamins, Amino Acids and Coenzymes
Grade Standard:
Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade
Usage:
Animal Pharmaceuticals
Brand Name:
LOOK
Model Number:
CB50-14-6
Purity:
99%
Appearance::
White Crystalline Powder
Melting point::
115-119℃
Assay::
99%
Storage::
cool dry place
Shelf life::
2 Years
Packaging&Delivery
Port
QINGDAO

Property

CAS No.: 50-14-6 Formula: C28H44O Molecular Weight: 396.64800

Description

Ergocalciferol (vitamin D2) is a form of vitamin D. Ergocalciferol is a secosteroid formed by a photochemical bond breaking of a steroid, specifically, by the action of ultraviolet light on ergosterol. Viosterol, the name given to early preparations of irradiated ergosterol, is essentially synonymous with ergocalciferol.
Ergocalciferol may be used as a vitamin D supplement, and a 2011 clinical guideline considered ergocalciferol to be as effective as cholecalciferol (vitamin D3) which is produced naturally by the skin when exposed to ultraviolet light. Ergocalciferol is manufactured and marketed under various names, including Deltalin (Eli Lilly and Company), Drisdol (Sanofi-Synthelabo) and Calcidol (Patrin Pharma).

Basic Info

Chemical Name	Vitamin D2
Synonyms	Calciferol,Ercalciol,Ergocalciferol; Daral; Infron; Ergocalciferol; Ertron; Irradiated ergosterol; Decaps; Vitamin D2; Buco-D; calciferol; (3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol; Condol; Ergosterol irradiated; Crtron; (5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol; 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3β,5Z,7E,22E)-; Ergocalciferol(D2); Vio-D; Calciferol,Ercalciol,Ergosterol irradiated; Doral; minad2;
CAS No.	50-14-6
Molecular Formula	C28H44O
Molecular Weight	396.64800
PSA	20.23000
LogP	7.64100

Properties

Appearance & Physical State	odorless white crystals
Density	0.97 g/cm3
Boiling Point	504.2ºC at 760 mmHg
Melting Point	115-119ºC
Flash Point	218.2ºC
Refractive Index	1.53
Storage Condition	2-8ºC

Safety Info

RTECS	KE1050000
Hazard Class	6.1(a)
Safety Statements	S28-S36/37-S45
Packing Group	II
WGK Germany	3
RIDADR	UN 2811
Risk Statements	R24/25; R26; R48/25
Hazard Codes	T+
Signal Word	Danger
Caution Statement	P260; P280; P302 + P352 + P312; P304 + P340 + P310; P403 + P233
Hazard Declaration	H301 + H311; H330; H372
Symbol	GHS06, GHS08

Synthesis Route

(1R,3aR,4R,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-4-[(1R,2Z)-1-hydroxy-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ol→Vitamin D2
(3β,5Z,7R,8α,22E)-3S-tert-Butyldimethylsilyl-9,10-secoergosta-5,10(19),22-triene-7,8-diol→Vitamin D2
(1R,3aR,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-one→Vitamin D2

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Human - woman	12600 ug/kg/72W	1.Behavioral-anorexia (human) 2.Gastrointestinal-nausea or vomiting 3.Nutritional and Gross Metabolic-weight loss or decreased weight gain
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	10 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	23700 ug/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

[1R-[1α,(1R*,2E,4R*),3aβ,4α,7aα]]-4-[(Benzothiazol-2-yl)sulfanyl]octahydro-7a-methyl-1-(1,4,5-trimethylhex-2-enyl)-1H-indene
[1R-[1α,(1R*,2E,4R*),3aβ,4β,7aα]]-Octahydro-7a-methyl-1-(1,4,5-trimethylhex-2-enyl)-1H-inden-4-ol
(1R,3aR,4R,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-4-[(1R,2Z)-1-hydroxy-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ol
(1R,3aR,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-one

Downstream Product

toxisterol2 R
calcitriol
(3S,5Z,7E,14ξ,22E)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-9, 10-secoergosta-5,7,10,22-tetraene
dihydrotachysterol

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