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vigabatrin

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Origin: China

Cas No: 60643-86-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 60643-86-9 Formula: C6H11NO2 Molecular Weight: 129.15700

    Description

    Vigabatrin, also known as gamma-vinyl-GABA, is an antiepileptic drug that inhibits the breakdown of γ-aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA receptors. It is sold under the brand name Sabril.

    Basic Info

    Chemical Name vigabatrin
    Synonyms

    VIGABATRIN;
    (±)-Vigabatrin;

    CAS No. 60643-86-9
    Molecular Formula C6H11NO2
    Molecular Weight 129.15700
    PSA 63.32000
    LogP 1.06480

    Properties

    Density 1.108 g/mL at 25 °C(lit.)
    Boiling Point 73 °C749 mm Hg(lit.)
    Flash Point 16 °F
    Refractive Index n20/D 1.319(lit.)
    Storage Condition Desiccate at +4ºC

    Safety Info

    RTECS MP7745000
    Safety Statements S26-S36
    HS Code 2922499990
    WGK Germany 2
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    5-Vinylpyrrolidone→vigabatrin
    4-benzenesulphonamido 5-hexenoic acid→vigabatrin
    4-(carbobenzyloxy)amino-5-hexenenitrile→vigabatrin

    Precursor

    4-benzenesulphonamido 5-hexenoic acid
    ethyl hex-5-enoate
    4-(carbobenzyloxy)amino-5-hexenenitrile
    5-Vinylpyrrolidone

    Downstream Product

    4-amino-5-fluorohex-5-enoic acid
    5-Vinylpyrrolidone

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