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tranexamic acid

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Origin: China

Cas No: 1197-18-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
1197-18-8
Other Names:
TRANS-4-AMINOMETHYL-1-CYCLOHEXANECARBOXYLIC ACID
MF:
C8H15NO2
EINECS No.:
214-818-2
Place of Origin:
China
Type:
Anesthetic Agents, Antidote, Blood System Agents, Cardiovascular Agents, Central Nervous System Agents, Auxiliaries and Other Medicinal Chemicals
Grade Standard:
Cosmetic Grade, Medicine Grade, Tech Grade
Brand Name:
Chuangying
Model Number:
CY-1197-18-8
Purity:
99.8min
Certificate:
ISO
Shelf life:
1-2 Year
Storage:
Cool Dry Place
Sample:
Availiable
Form:
Powder Form
Test Method:
PHLC
Package:
25kg/carton Drum or customized
Delivery time:
3-7 Days
Shipment:
Sea
Packaging&Delivery
Packaging Details
25 kg/ drum or customized
Port
Shanghai Qingdao
Lead Time:
Quantity(Kilograms) 1 - 1000 >1000
Est. Time(days) 7 To be negotiated

Property

CAS No.: 1197-18-8 Formula: C8H15NO2 Molecular Weight: 157.21000

Description

Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. It comes in oral and intravenous forms.
Side effects are uncommon and include gastrointestinal effects, dizziness, fatigue, headache, and hypersensitivity reactions. The medication needs to be used cautiously in people with kidney disease and who are at a high risk for blood clots. Tranexamic is safe to use in pregnant women. However, caution should be used in lactating women. It is an antifibrinolytic.
It was discovered in 1962 by Utako Okamoto and has been on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Basic Info

Chemical Name	tranexamic acid
Synonyms	Amstat; Tranexamic acid; Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-; trans-4-(Aminomethyl)cyclohexanecarboxylic acid; AMCA,AMCHA,HAKU;
CAS No.	1197-18-8
Molecular Formula	C8H15NO2
Molecular Weight	157.21000
PSA	63.32000
LogP	1.53640

Properties

Appearance & Physical State	white crystalline powder
Density	1.096g/cm3
Boiling Point	300.201ºC at 760 mmHg
Melting Point	300ºC
Flash Point	135.357ºC
Refractive Index	1.497
Stability	Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition	Refrigerator
Vapor Pressure	0mmHg at 25°C

Safety Info

Hazard Class	3
Safety Statements	S26; S36; S37/39
HS Code	2922499990
Packing Group	II
WGK Germany	2
RIDADR	UN 1993 3/PG 2
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

(1r,4r)-4-((3-carboxyacrylamido)methyl)cyclohexane-1-carboxylic acid→maleic anhydride+tranexamic acid
methyl trans-4-cyanocyclohexane-1-carboxylate→tranexamic acid

Precursor

methyl trans-4-cyanocyclohexane-1-carboxylate
(1r,4r)-4-((3-carboxyacrylamido)methyl)cyclohexane-1-carboxylic acid

Downstream Product

cetraxate
ethyl 4-(aminomethyl)cyclohexane-1-carboxylate
trans-4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid
Boc-trans-4-(aminomethyl)-cyclohexane-1-carboxylic acid

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