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Tozasertib

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Origin: China

Cas No: 639089-54-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 639089-54-6 Formula: C23H28N8OS Molecular Weight: 464.58600

    Description

    VX-680 is an aurora inhibitor.

    Basic Info

    Chemical Name Tozasertib
    Synonyms

    N-(4-((4-((3-methyl-1H-pyrazol-5-yl)amino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide;
    Tozasertib Free Base;
    MK-0457;
    VX-680;

    CAS No. 639089-54-6
    Molecular Formula C23H28N8OS
    Molecular Weight 464.58600
    PSA 127.37000
    LogP 3.65210

    Properties

    Density 1.37 g/cm3
    Refractive Index 1.708

    Synthesis Route

    1-Methylpiperazine+N-[4-[4-chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide→Tozasertib

    Precursor

    1-Methylpiperazine
    N-[4-[4-chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide

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