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Tiapride hydrochloride

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Origin: China

Cas No: 51012-32-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 51012-32-9 Formula: C15H25ClN2O4S Molecular Weight: 364.88800

    Description

    Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. It is used to treat a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. A derivative of benzamide, tiapride is chemically and functionally similar to other benzamide antipsychotics such as sulpiride and amisulpride known for their dopamine antagonist effects.

    Basic Info

    Chemical Name Tiapride hydrochloride
    Synonyms

    N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-o-anisamide hydrochloride;
    N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide;
    N-(2-(Diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamide;

    CAS No. 51012-32-9
    Molecular Formula C15H25ClN2O4S
    Molecular Weight 364.88800
    PSA 84.09000
    LogP 3.44400

    Properties

    Density 1.15 g/cm3
    Boiling Point 498.1ºC at 760 mmHg
    Melting Point 120ºC
    Flash Point 255.1ºC
    Stability Stable at normal temperatures and pressures.
    Storage Condition 2-8ºC

    Safety Info

    RTECS CV4203800
    HS Code 2924299090
    WGK Germany 2

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed SE-30 280. 2850. isothermal

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Subcutaneous TDLo - Lowest published toxic dose Rodent - rat 1197 mg/kg,female 38 day(s) pre-mating 1.Reproductive-Maternal Effects-uterus, cervix, vagina
    Subcutaneous TDLo - Lowest published toxic dose Rodent - rat 850 mg/kg,female 27 day(s) pre-mating 1.Reproductive-Maternal Effects-menstrual cycle changes or disorders

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