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Thiothiamine

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Origin: China

Cas No: 299-35-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 299-35-4 Formula: C12H16N4OS2 Molecular Weight: 296.41200

    Description

    Thiothiamine is an impurity of Thiamine. Thiothiamine inhibits the activity of glutamate decarboxylase and decreases the concentration of GABA in brain tissue. Thiamine Impurity A;

    Basic Info

    Chemical Name Thiothiamine
    Synonyms

    3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione;
    3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazol-2(3H)-thione;
    Thiamine impurity E;

    CAS No. 299-35-4
    Molecular Formula C12H16N4OS2
    Molecular Weight 296.41200
    PSA 137.29000
    LogP 2.43240

    Properties

    Density 1.42g/cm3
    Boiling Point 509.6ºC at 760mmHg
    Flash Point 262ºC
    Refractive Index 1.709
    Vapor Pressure 3.28E-11mmHg at 25°C

    Synthesis Route

    thiamine(2+) dichloride3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one+Thiothiamine
    isobutanol+thiamine disulfide3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one+Thiothiamine
    isobutanol+3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one+Thiothiamine

    Precursor


    thiamine(2+) dichloride
    Thiamine ion
    thiamine disulfide

    Downstream Product

    Vitamin B1
    Thiamine ion
    3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
    Thiamine nitrate

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