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Thieno[3,2-c]pyridine

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Origin: China

Cas No: 272-14-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 272-14-0 Formula: C7H5NS Molecular Weight: 135.18600

Description

An intermediate of Ticlopidine. Thieno[3,2-c]pyridine derivatives are used for treatment of inflammatory disorders.

Basic Info

Chemical Name	Thieno[3,2-c]pyridine
Synonyms	thieno[3,2-c]pyridine;
CAS No.	272-14-0
Molecular Formula	C7H5NS
Molecular Weight	135.18600
PSA	41.13000
LogP	2.29630

Properties

Density	1.272g/cm3
Boiling Point	255.1ºC at 760mmHg
Melting Point	47-49ºC
Flash Point	112.3ºC
Refractive Index	1.689
Vapor Pressure	0.0266mmHg at 25°C

Safety Info

HS Code	2934999090

Synthesis Route

7-methoxy-4,5,6,7-tetrahydro-thieno(3,2-c)pyridine hydrochloride+p-Toluenesulfonyl chloride→Thieno[3,2-c]pyridine
N-(2,2-dimethoxyethyl)-4-methyl-N-3-(thienylmethyl)benzenesulfonamide→Thieno[3,2-c]pyridine
2-vinylthiophene-3-carbaldehyde oxime→Thieno[3,2-c]pyridine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intravenous	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	205 mg/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

2-vinylthiophene-3-carbaldehyde oxime
N-(2,2-dimethoxyethyl)-4-methyl-N-3-(thienylmethyl)benzenesulfonamide
7-methoxy-4,5,6,7-tetrahydro-thieno(3,2-c)pyridine hydrochloride
p-Toluenesulfonyl chloride

Downstream Product

Thieno[3,2-c]pyridine-2-carboxylic acid
thieno[3,2-c]pyridine-4-carbonitrile
3-bromothieno[3,2-c]pyridine
5-oxidothieno[3,2-c]pyridin-5-ium

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