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tert-Butyl rosuvastatin

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Origin: China

Cas No: 355806-00-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    355806-00-7
    Other Names:
    tert-butyl rosuvastatin
    MF:
    C26H36FN3O6S
    EINECS No.:
    355806-00-7
    Place of Origin:
    china
    Type:
    Anesthetic Agents
    Grade Standard:
    Medicine Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    Richest
    Model Number:
    Richest
    Purity:
    99%min

    Packaging&Delivery

    Packaging Details
    1kg/bag,25kg/bag,25kg/drum or customer's request
    Port
    shanghai
    Lead Time:
    Quantity(Kilograms)1 - 25>25
    Est. Time(days)3To be negotiated

  • Property

    CAS No.: 355806-00-7 Formula: C26H36FN3O6S Molecular Weight: 537.64400

    Description

    Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin a selective, competitive HMG-CoA reductase inhibitor.

    Basic Info

    Chemical Name tert-Butyl rosuvastatin
    Synonyms

    Rosuvastatin calciuM interMediate R-3;
    Rosuvastatin intermediate R-3;
    Rosuvastatin tert-butyl ester;
    tert-Butyl rosuvasta;
    ZD-8;
    Rosuvastatin t-Butyl Ester;

    CAS No. 355806-00-7
    Molecular Formula C26H36FN3O6S
    Molecular Weight 537.64400
    PSA 138.30000
    LogP 4.73960

    Properties

    Appearance & Physical State white to off-white crystal powder
    Density 1.259
    Boiling Point 704.158ºC at 760 mmHg
    Flash Point 379.661ºC
    Refractive Index 1.564

    Safety Info

    HS Code 2935009090

    Synthesis Route

    tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate→tert-Butyl rosuvastatin
    tert-butyl-2((4R,6S)-6-{(E)-2-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfon-amido)-pyrimidin-5-yl]-vinyl}-2-phenyl-[1,3]dioxan-4-yl)acetate→tert-Butyl rosuvastatin
    (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(hydroxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester→tert-Butyl rosuvastatin

    Precursor

    tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
    tert-butyl 2-[6-[(E)-2-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate
    (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(hydroxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester
    tert-butyl-2((4R,6S)-6-{(E)-2-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfon-amido)-pyrimidin-5-yl]-vinyl}-2-phenyl-[1,3]dioxan-4-yl)acetate

    Downstream Product

    Rosuvastatin
    Rosuvastatin Lactone

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