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Origin: China
Cas No: 78628-80-5
Specification: 99%min
Min order Quantity: 1 /kg
Supply Ability: 80 mt/month
Lead time: 7 days for OEM, 3 days for ready goods
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Dermatologist Broad-spectrum Antifungal Drugs
Terbinafine hydrochloride is a kind of broad-spectrum dermatologist allyl amine antifungal drugs.Approved by FDA of the United States for OTC drugs in 1996, and appeared in the market of the United States in the same year. At present, the drug is been sold in more than 90 countries of the word. It can specificity trouble the late biological decomposition of fungus sterol, selectively inhibit the activity of fungal squalene ring oxidase, and inhibit the squalene epoxidation in the formation of ungal cell membrane, thus to kill or inhibit the active of the fungus. Suitable for treatment of candidiasis skin, such as tinea manuum, tinea, tinea, ringworm of the body, tinea versicolor, it is also the best medicine for the treatment of onychomycosis.
Terbinafine hydrochloride entered the the first batch of country announced OTC directory in 2000. This product belongs to antifungal drugs. It has strong effect on shallow fungal infection, and can cure most of the fungal skin diseases through external use.
Indications
1.Skin, hair and nail infection caused by Btrichophyta (white hair versicolor bacterium, Trichophyton mentagrophytes, Trichophyton verrucosum, trichophyton tonsurans and Trichophyton violaceum, etc.), microsporum canis, epidermophyton floccosum, ect.
2.Skin yeast infections caused by all kinds of tinea disease (ringworm of the body, tinea, tinea manus and tinea capitis, etc.) and candida (candida albicans, etc.).
3.Onychomycosis (nail fungus infection) caused by molds.
Property
Description
Basic Info
Chemical Name | terbinafine hydrochloride |
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Synonyms |
Terbinafine hydrochloride; |
CAS No. | 78628-80-5 |
Molecular Formula | C21H26ClN |
Molecular Weight | 327.89100 |
PSA | 3.24000 |
LogP | 5.67930 |
Properties
Appearance & Physical State | Crystalline powder |
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Density | 1.007g/cm3 |
Boiling Point | 417.9ºC at 760 mmHg |
Melting Point | 204-208ºC |
Flash Point | 183.7ºC |
Refractive Index | 1.586 |
Storage Condition | -20ºC Freezer |
Safety Info
RTECS | QJ8600100 |
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Safety Statements | S26; S36/37/39; S61; S60 |
HS Code | 2921499090 |
RIDADR | UN 3077 9/PG 3 |
Risk Statements | R36/37/38 |
Hazard Codes | Xi; N |
Caution Statement | P261; P273; P305 + P351 + P338; P501 |
Signal Word | Warning |
Hazard Declaration | H315; H319; H335; H410 |
Symbol | GHS07, GHS09 |
Synthesis Route
Precursor
Downstream Product