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Sunitinib Malate

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Origin: China

Cas No: 341031-54-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    cas no.341031-54-7
    Other Names:
    Methimazole
    MF:
    C4H6N2S
    Place of Origin:
    China
    Type:
    Antibiotic and Antimicrobial Agents
    Grade Standard:
    Medicine Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    Runyu
    Model Number:
    runyubio
    Purity:
    98.5%
    Product Name:
    Methimazole
    Appearance:
    White Powder
    Grade:
    medicine Grade
    Specification:
    98.5%
    Synonyms::
    2-Mercapto-1-MethyliMidazole
    Fuction:
    Anti-wrinkle & Anti-aging
    test method:
    HPLC
    usuage:
    intermediates

    Packaging&Delivery

    Packaging Details
    25kilograms per cardboard barrel; inside packing : double food plastic bags; outside packing : cardboard barrel
    1kilograms per box; inside packing : double food plastic bags+foil; outside packing : box
    Port
    TIANJIN;SHANGHAI;QINGDAO;DALIAN
    Lead Time:
    Quantity(Grams)1 - 1>1
    Est. Time(days)5To be negotiated
  • Property

    CAS No.: 341031-54-7 Formula: C26H33FN4O7 Molecular Weight: 532.56100

    Description

    Sunitinib (marketed as Sutent by Pfizer, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib was the first cancer drug simultaneously approved for two different indications.

    Basic Info

    Chemical Name Sunitinib Malate
    Synonyms

    sunitinib L-malic acid salt;
    Sunitinib malate;
    sunitynib L-malate;
    L-malic acid salt of sunitinib;

    CAS No. 341031-54-7
    Molecular Formula C26H33FN4O7
    Molecular Weight 532.56100
    PSA 172.06000
    LogP 2.77040

    Properties

    Density 1.229g/cm3
    Boiling Point 572.1ºC at 760mmHg
    Flash Point 299.8ºC
    Refractive Index n20/D 1.455(lit.)

    Safety Info

    Safety Statements S24/25
    WGK Germany 3
    Risk Statements R36/37/38

    Synthesis Route

    (S)-malic acid+5-fluoro-1-(trimethylsilyl)-2-(trimethylsilyloxy)-1H-indoleSunitinib Malate
    5-Fluoro-2-oxindole+L-(-)-malic acid of 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amideSunitinib Malate
    5-Fluoro-2-oxindole+(S)-malic acidSunitinib Malate

    Precursor

    5-Fluoro-2-oxindole
    L-(-)-malic acid of 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide
    5-fluoro-1-(trimethylsilyl)-2-(trimethylsilyloxy)-1H-indole
    N-[2-(diethylamino)ethyl]-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide

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