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sphingosine 1-phosphate

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Origin: China

Cas No: 26993-30-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 26993-30-6 Formula: C18H38NO5P Molecular Weight: 379.47200

Description

Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is also referred to as a bioactive lipid mediator. Sphingolipids at large form a class of lipids characterized by a particular aliphatic aminoalcohol, which is sphingosine.

Basic Info

Chemical Name	sphingosine 1-phosphate
Synonyms	(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-phosphate D-erythro-Sphingosine 1-phosphate; S1P; [(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enyl] dihydrogen phosphate; Sphing-4-enine 1-phosphate; Sphingosine 1-phosphic acid; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-phosphate,D-erythro-Sphingosine 1-phosphate; D-erythro-Sphingosine 1-phosphate; Somatostatin 1-28; C18-Sphingosine 1-phosphate; D-erythro-sphingosine-1-phosphate; Sphingosine 1-phosphate;
CAS No.	26993-30-6
Molecular Formula	C18H38NO5P
Molecular Weight	379.47200
PSA	122.82000
LogP	4.74150

Properties

Appearance & Physical State	Off-white to grey powder
Density	1.094g/cm3
Boiling Point	548.8ºC at 760 mmHg
Melting Point	190ºC
Flash Point	285.7ºC
Refractive Index	1.501
Storage Condition	-20ºC
Vapor Pressure	2.49E-14mmHg at 25°C

Safety Info

Safety Statements	26-36
HS Code	2922509090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

tert-butyl ((2S,3R,E)-1-((dimethoxyphosphoryl)oxy)-3-hydroxyoctadec-4-en-2-yl)carbamate→sphingosine 1-phosphate
(2S,3R)-2-amino-octadec-4-ene-3-(t-butyl-diphenylsilyloxy)-1-ol-phosphate→sphingosine 1-phosphate
((2S,3R,4E)-2-amino-3-(tert-butyldimethylsilyloxy)-4-octadecene-1-yl) dihydrogen phosphate→sphingosine 1-phosphate

Precursor

N-Boc-erythro-sphingosine
(2S,3R)-2-amino-octadec-4-ene-3-(t-butyl-diphenylsilyloxy)-1-ol-phosphate
tert-butyl ((2S,3R,E)-1-((dimethoxyphosphoryl)oxy)-3-hydroxyoctadec-4-en-2-yl)carbamate
tert-butyl (4S,5R,1'E)-4-(hydroxymethyl)-2,2-dimethyl-5-(pentadec-1'-enyl)-oxazolidine-3-carboxylate

Downstream Product

N-Biotinyl D-erythro-Sphingosine-1-phosphate

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