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(S)-(-)-PROPRANOLOL HYDROCHLORIDE

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Origin: China

Cas No: 4199-10-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 4199-10-4 Formula: C16H22ClNO2 Molecular Weight: 295.80400

Description

The S-enantiomer of Propranolol. β−Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).

Basic Info

Chemical Name	(S)-(-)-PROPRANOLOL HYDROCHLORIDE
Synonyms	dl-propranololHClbp; PROPRANOLOL HCL; dl-propranolol hcl; dl-propranololhydrochloridebp; PENTAPROPANOLOLHYDROCHLORIDE; Sazetidine A dihydrochloride; DL-PROPRANOLOL HYDROCHLORIDE; PROPANOLOL HYDROCHLORIDE; L-Propranololhydrochlorid;
CAS No.	4199-10-4
Molecular Formula	C16H22ClNO2
Molecular Weight	295.80400
PSA	41.49000
LogP	3.77040

Properties

Boiling Point	434.9ºC at 760mmHg
Melting Point	193-195ºC(lit.)
Flash Point	216.8ºC
Storage Condition	2-8ºC

Safety Info

Safety Statements	S36
HS Code	2906199090
Risk Statements	R20/21/22
Hazard Codes	Xn

Synthesis Route

propranolol hydrochloride→(S)-(-)-PROPRANOLOL HYDROCHLORIDE+propranolol hydrochloride
1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-one hydrochloride→(S)-(-)-PROPRANOLOL HYDROCHLORIDE
1-naphthol+(S)-Glycidyl 3-Nitrobenzenesulfonate→(S)-(-)-PROPRANOLOL HYDROCHLORIDE

Precursor

(2RS,4R)-4-(1-naphthyloxy)methyl-2-oxo-1,3,2-dioxathiolane
isopropylamine
1-naphthol
(S)-Glycidyl 3-Nitrobenzenesulfonate

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