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(S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone

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Origin: China

Cas No: 152305-23-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
152305-23-2
MF:
C10H12N2O2
Place of Origin:
CHINA
Type:
Pharmaceutical Intermediates
Purity:
98%MIN
Brand Name:
Royal pharm
Application:
Used
Appearance:
solid
MW:
192.21
Packaging&Delivery
Packaging Details
Drum&plastic bags or Aluninium foiled bag&zip lock bag
Port
HangZhou
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 3 To be negotiated

Property

CAS No.: 152305-23-2 Formula: C10H12N2O2 Molecular Weight: 192.21400

Description

An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase.

Basic Info

Chemical Name	(S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone
Synonyms	ZTR 5; (S)-4-(4-Aminobenzyl)-2-oxazolidinone; (S)-4-(4-Aminobenzyl)oxazolidin-2-one; (S)-4-(4-Aminobenzyl)-2(1H)-Oxazolidinone;
CAS No.	152305-23-2
Molecular Formula	C10H12N2O2
Molecular Weight	192.21400
PSA	64.35000
LogP	1.82970

Properties

Appearance & Physical State	white crystalline powder
Density	1.257g/cm3
Boiling Point	479.7ºC at 760 mmHg
Melting Point	107-111ºC
Flash Point	243.9ºC
Refractive Index	-6.0 ° (C=1, MeOH)
Vapor Pressure	0mmHg at 25°C

Safety Info

Safety Statements	S26-S36/37
WGK Germany	2
Risk Statements	R22; R36/37/38
Hazard Codes	Xn

Synthesis Route

(S)-4-(4-Nitrobenzyl)oxazolidin-2-one→(S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone
(S)-2-amino-3-(4-aminophenyl)propanol+Diethyl carbonate→(S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone
L-phenylalanine→(S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone

Precursor

L-phenylalanine
(S)-2-amino-3-(4-aminophenyl)propanol
(S)-4-(4-Nitrobenzyl)oxazolidin-2-one
(2S)-2-amino-3-(4-nitrophenyl)propanoic acid

Downstream Product

zolmitriptan
ethyl 3-[2-(dimethylamino)ethyl]-5-[[(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl]-1H-indole-2-carboxylate

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