Home > Organic Nitrogen Compounds> (S)-1-Boc-3-(Hydroxymethyl)piperazine

(S)-1-Boc-3-(Hydroxymethyl)piperazine

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Origin: China

Cas No: 314741-40-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 314741-40-7 Formula: C10H20N2O3 Molecular Weight: 216.27700

Basic Info

Chemical Name	(S)-1-Boc-3-(Hydroxymethyl)piperazine
Synonyms	(S)-tert-Butyl 3-(hydroxymethyl)piperazine-1-carboxylate; tert-butyl (3S)-3-(hydroxymethyl)piperazine-1-carboxylate;
CAS No.	314741-40-7
Molecular Formula	C10H20N2O3
Molecular Weight	216.27700
PSA	61.80000
LogP	0.45430

Properties

Density	1.085g/cm3
Boiling Point	322.9ºC at 760 mmHg
Flash Point	149.1ºC
Refractive Index	1.477

Safety Info

HS Code	2933599090

Synthesis Route

1-O-tert-butyl 3-O-methyl (3S)-piperazine-1,3-dicarboxylate→(S)-1-Boc-3-(Hydroxymethyl)piperazine
(2S)-4-[(2-methylpropan-2-yl)oxycarbonyl]piperazine-2-carboxylic acid→(S)-1-Boc-3-(Hydroxymethyl)piperazine
tert-butoxycarbonyl anhydride+(S)-2-HYDROXYMETHYL-PIPERAZINE→(S)-1-Boc-3-(Hydroxymethyl)piperazine

Precursor

1-O-tert-butyl 3-O-methyl (3S)-piperazine-1,3-dicarboxylate
tert-butoxycarbonyl anhydride
(2S)-4-[(2-methylpropan-2-yl)oxycarbonyl]piperazine-2-carboxylic acid
tert-butyl (8aS)-3-oxotetrahydro-1,3-oxazolo[3,4-a]pyrazine-7(1H)-carboxylate

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