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Rotigotine Hydrochloride

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Origin: China

Cas No: 125572-93-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 125572-93-2 Formula: C19H26ClNOS Molecular Weight: 351.93400

Description

It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.

Basic Info

Chemical Name	Rotigotine Hydrochloride
Synonyms	(6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol,hydrochloride;
CAS No.	125572-93-2
Molecular Formula	C19H26ClNOS
Molecular Weight	351.93400
PSA	51.71000
LogP	5.06770

Properties

Appearance & Physical State	Almost white to white crystalline powder
Boiling Point	470.1ºC at 760 mmHg
Melting Point	186.5-187.5ºC
Flash Point	238.1ºC
Vapor Pressure	1.84E-09mmHg at 25°C

Safety Info

HS Code	2942000000

Synthesis Route

(2S)-5-methoxy-N-propyl-N-(2'-(thien-2-yl)ethyl)tetralin-2-amine hydrochloride→Rotigotine Hydrochloride
[14C]-Rotigotine→Rotigotine Hydrochloride
(2S)-5-methoxy-N-propyl-N-(2'-(thien-2-yl)ethyl)tetralin-2-amine→Rotigotine Hydrochloride

Precursor

(R)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-naphthalen-2-amine
[14C]-Rotigotine
5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine,hydrochloride
(2S)-5-methoxy-N-propyl-N-(2'-(thien-2-yl)ethyl)tetralin-2-amine

Downstream Product

[14C]-Rotigotine

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