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rivaroxaban

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Origin: China

Cas No: 366789-02-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 366789-02-8 Formula: C19H18ClN3O5S Molecular Weight: 435.88100

    Description

    A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.

    Basic Info

    Chemical Name rivaroxaban
    Synonyms

    Rivaroxaban;
    BAY 59-7939;
    Rivarobaxan;
    Xarelto;
    Rivaroxaba;
    rivaraoxaban;

    CAS No. 366789-02-8
    Molecular Formula C19H18ClN3O5S
    Molecular Weight 435.88100
    PSA 116.42000
    LogP 3.04080

    Properties

    Density 1.46g/cm3
    Boiling Point 732.6ºC at 760mmHg
    Melting Point 228-229°C
    Flash Point 396.9ºC
    Refractive Index 1.633

    Synthesis Route

    5-Chlorothiophene-2-carbonyl chloride+(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride→rivaroxaban
    →rivaroxaban
    5-Chlorothiophene-2-carbonyl chloride+→rivaroxaban

    Precursor

    5-Chlorothiophene-2-carbonyl chloride
    (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride

    5-chloro-N-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-2-thiophenecarboxamide

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