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raloxifene hydrochloride

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Origem: China

Cas No: 82640-04-8

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Especificação de produtos
Descrição do produto

Property

CAS No.: 82640-04-8 Formula: C28H28ClNO4S Molecular Weight: 510.04400

Description

A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic. Insoluble in water.

Basic Info

Chemical Name	raloxifene hydrochloride
Synonyms	Raloxifene Hydrochloride;
CAS No.	82640-04-8
Molecular Formula	C28H28ClNO4S
Molecular Weight	510.04400
PSA	98.24000
LogP	6.81510

Properties

Appearance & Physical State	Light yellow solid
Density	1.285g/cm3
Boiling Point	728.2ºC at 760 mmHg
Melting Point	143-147ºC
Flash Point	394.2ºC
Refractive Index	1.654
Storage Condition	-20ºC Freezer

Safety Info

Safety Statements	S22; S24/25
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

[4-(6-acetyloxy-1-benzothiophen-2-yl)phenyl] acetate+4-[2-(1-Pipiridine)ethoxybenzoic acid hydrochloride→raloxifene hydrochloride
[6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophen-3-yl]{4-[2-(1-pipe ridinyl)ethoxy]phenyl}methanone hydrochloride (1:1)→raloxifene hydrochloride
6-Methoxy-2-(4-methoxyphenyl)benzo[b]thiophene+4-[2-(1-Pipiridine)ethoxybenzoic acid hydrochloride→raloxifene hydrochloride

Precursor

4-[2-(1-Pipiridine)ethoxybenzoic acid hydrochloride
[6-[(methylsulfonyl)oxy]-2-[4-[(methylsulfonyl)oxy]phenyl]benzo[b]thien-3-yl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone hydrochloride
[4-(6-acetyloxy-1-benzothiophen-2-yl)phenyl] acetate
[6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophen-3-yl]{4-[2-(1-pipe ridinyl)ethoxy]phenyl}methanone hydrochloride (1:1)

Downstream Product

raloxifene

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