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rac 5-Carboxy Tolterodine

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Origin: China

Cas No: 1076199-77-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 1076199-77-3 Formula: C22H29NO3 Molecular Weight: 355.47100

Description

A metabolite of Tolterodine. Also, a degradation product of Fesoterodine formed under stress conditions in tablet dosage forms.

Basic Info

Chemical Name	rac 5-Carboxy Tolterodine
Synonyms	3-[3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxybenzoic acid;
CAS No.	1076199-77-3
Molecular Formula	C22H29NO3
Molecular Weight	355.47100
PSA	60.77000
LogP	4.73120

Synthesis Route

(R)-N,N-diisopropyl-3-phenyl-3-(5-formyl-2-hydroxyphenyl)propyl-1-amine→rac 5-Carboxy Tolterodine
(E)-3-phenyl-N,N-di(propan-2-yl)prop-2-en-1-amine+4-Hydroxybenzoic acid→rac 5-Carboxy Tolterodine
4-Bromophenol→rac 5-Carboxy Tolterodine

Precursor

4-Bromophenol
cinnamic acid
(E)-3-phenyl-N,N-di(propan-2-yl)prop-2-en-1-amine
4-Hydroxybenzoic acid

Downstream Product

[2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate
5-hydroxymethyl Tolterodine

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