Home > Organic Nitrogen Compounds> (R)-(-)-3-Pyrrolidinol hydrochloride

(R)-(-)-3-Pyrrolidinol hydrochloride

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Origin: China

Cas No: 104706-47-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 104706-47-0 Formula: C4H10ClNO Molecular Weight: 123.58100

Description

(R)-(-)-3-Hydroxypyrrolidine is a chiral hydroxy derivative of pyrrlodine used in the preparation of chiral niologically active compounds such as muscarinic receptor antagonists and antimicrobial agents.

Basic Info

Chemical Name	(R)-(-)-3-Pyrrolidinol hydrochloride
Synonyms	(R)-(-)-3-Hydroxypyrrolidine Hydrochloride; (R)-(-)-3-Pyrrolidinol Hydrochloride; (3R)-pyrrolidin-3-ol,hydrochloride; (R)-3-Pyrrolidinol hydrochloride; (R)-3-Hydroxypyrrolidine hydrochloride; R-3-Hydroxypyrrolidine Hcl;
CAS No.	104706-47-0
Molecular Formula	C4H10ClNO
Molecular Weight	123.58100
PSA	32.26000
LogP	0.47140

Properties

Boiling Point	224.7ºC at 760 mmHg
Melting Point	106-109ºC
Refractive Index	-7.8 ° (C=3.5, MeOH)

Safety Info

Safety Statements	S26-S36
HS Code	2933990090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

4-hydroxy-L-proline→(R)-(-)-3-Pyrrolidinol hydrochloride
1-Boc-(R)-(-)-3-Hydroxypyrrolidine→(R)-(-)-3-Pyrrolidinol hydrochloride
2-Chloro-5-trifluoromethylpyridine→1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidin-3(R)-ol+(R)-(-)-3-Pyrrolidinol hydrochloride

Precursor

1-Boc-(R)-(-)-3-Hydroxypyrrolidine
4-hydroxy-L-proline
2-Chloro-5-trifluoromethylpyridine

Downstream Product

N-Cbz-3-hydroxypyrrolidine
1-(3-fluorophenyl)pyrrolidin-3-ol
(R)-3-Hydroxy-1-methyl-pyrrolidine
(R)-1-Carbobenzoxy-3-pyrrolidinol

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