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Home > Chiral Compounds> (R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester
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(R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester

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Origin: China

Cas No: 215917-99-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 215917-99-0 Formula: C10H19NO4 Molecular Weight: 217.26200

    Description

    An intermediate of BMS-599626, a selective and orally efficacious inhibitor of human epidermal growth factor receptor 1 and 2 kinases.

    Basic Info

    Chemical Name (R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester
    Synonyms

    tert-Butyl (3R)-3-(hydroxymethyl)morpholine-4-carboxylate;

    CAS No. 215917-99-0
    Molecular Formula C10H19NO4
    Molecular Weight 217.26200
    PSA 59.00000
    LogP 0.55250

    Properties

    Density 1.118g/cm3
    Boiling Point 320.7ºC at 760mmHg
    Flash Point 147.8ºC
    Refractive Index 1.474
    Vapor Pressure 2.53E-05mmHg at 25°C

    Safety Info

    HS Code 2934999090

    Synthesis Route

    (R)-(4-benzylmorpholin-3-yl)methanol hydrochloride+tert-butoxycarbonyl anhydride→(R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester
    tert-butoxycarbonyl anhydride+(R)-(4-Benzylmorpholin-3-yl)methanol→(R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester

    Precursor

    (R)-(4-benzylmorpholin-3-yl)methanol hydrochloride
    tert-butoxycarbonyl anhydride
    (R)-(4-Benzylmorpholin-3-yl)methanol

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