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Picture of (R)-1-Tosyloxy-2,3-propanediol

(R)-1-Tosyloxy-2,3-propanediol

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Origin: China

Cas No: 41274-09-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 41274-09-3 Formula: C10H14O5S Molecular Weight: 246.28000

    Description

    A chiral synthon for general asymmetric synthesis. An intermediate for the synthesis of chiral aryloxypropanolamines, which make up the majority of known potent beta-adrenergic blockers.

    Basic Info

    Chemical Name (R)-1-Tosyloxy-2,3-propanediol
    Synonyms

    [(2R)-2,3-dihydroxypropyl] 4-methylbenzenesulfonate;

    CAS No. 41274-09-3
    Molecular Formula C10H14O5S
    Molecular Weight 246.28000
    PSA 92.21000
    LogP 1.13430

    Properties

    Density 1.351 g/cm3
    Boiling Point 463ºC at 760 mmHg
    Melting Point 54-59ºC
    Refractive Index 1.559
    Storage Condition -20ºC

    Safety Info

    Safety Statements S26; S36
    HS Code 2905499000
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate(R)-1-Tosyloxy-2,3-propanediol
    (R)-(-)-3-tosyloxy-2-benzyloxy-1-propanol(R)-1-Tosyloxy-2,3-propanediol
    p-Toluenesulfonyl chloride(R)-1-Tosyloxy-2,3-propanediol

    Precursor

    [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate
    (R)-(-)-3-tosyloxy-2-benzyloxy-1-propanol
    p-Toluenesulfonyl chloride
    (R)-1-O-Acetyl-2-O-benzyl-3-tosylglycerol

    Downstream Product

    (S)-3-Amino-1,2-propanediol
    [(2R)-2-hydroxy-3-phenylmethoxypropyl] 4-methylbenzenesulfonate
    (R)-glycidol

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