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(R)-1-BOC-3-(Aminomethyl)piperidine

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Origin: China

Cas No: 140645-23-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 140645-23-4 Formula: C11H22N2O2 Molecular Weight: 214.30500

Basic Info

Chemical Name	(R)-1-BOC-3-(Aminomethyl)piperidine
Synonyms	(R)-tert-Butyl 3-(aminomethyl)piperidine-1-carboxylate; (R)-1-Boc-3-(aminomethyl)piperidine; (R)-3-Aminomethyl-1-Boc-piperidine; (R)-1-N-Boc-3-(aminomethyl)piperidine;
CAS No.	140645-23-4
Molecular Formula	C11H22N2O2
Molecular Weight	214.30500
PSA	55.56000
LogP	2.23040

Properties

Density	1.023g/cm3
Boiling Point	299.4ºC at 760mmHg
Flash Point	134.9ºC
Refractive Index	1.482
Vapor Pressure	0.001mmHg at 25°C

Safety Info

HS Code	2933399090
Hazard Codes	Xi
Symbol	GHS07, GHS09
Signal Word	Warning
Caution Statement	P261; P273; P305 + P351 + P338
Hazard Declaration	H302; H315; H319; H335; H400

Synthesis Route

tert-butyl (3S)-3-(azidomethyl)piperidine-1-carboxylate→(R)-1-BOC-3-(Aminomethyl)piperidine
(S)-1-BOC-3-(Hydroxymethyl)piperidine→(R)-1-BOC-3-(Aminomethyl)piperidine
(S)-[[(methylsulfonyl)oxy]methyl]piperidine-1-carboxylic acid tert-butyl ester→(R)-1-BOC-3-(Aminomethyl)piperidine

Precursor

(S)-[[(methylsulfonyl)oxy]methyl]piperidine-1-carboxylic acid tert-butyl ester
tert-butyl (3S)-3-(azidomethyl)piperidine-1-carboxylate
(S)-1-BOC-3-(Hydroxymethyl)piperidine

Downstream Product

(R)-1-Boc-3-(Cbz-amino-methyl)-piperidine

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