Polymyxin B sulfate is similar to polymyxin E, and it can inhibit gram-negative bacilli, such as Escherichia coli, Pseudomonas aeruginosa, Para Escherichia coli, Klebsiella pneumoniae, Acidophilus, Pertussis and Shigella, etc. Or bactericidal effect. It is mainly used for infection of wounds, urinary tract, eyes, ears, trachea and other parts caused by Pseudomonas aeruginosa and other pseudomonas. It can also be used for sepsis and peritonitis. And resistant to aminoglycosides, resistant to third-generation cephalosporin bacteria and Pseudomonas aeruginosa or other sensitive bacteria caused by serious infections, such as bacteremia, endocarditis, pneumonia, infection after burns, etc.