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polidocanol

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Origin: China

Cas No: 3055-99-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 3055-99-0 Formula: C30H62O10 Molecular Weight: 582.80700

    Description

    Polidocanol is a local anaesthetic and antipruritic component of ointments and bath additives. It relieves itching caused by eczema and dry skin. It is formed by the ethoxylation of dodecanol.
    The substance is also used as a sclerosant, an irritant injected to treat varicose veins, under the trade names Asclera, Aethoxysklerol and Varithena. Polidocanol causes fibrosis inside varicose veins, occluding the lumen of the vessel, and reducing the appearance of the varicosity.
    The FDA has approved polidocanol injections for the treatment of small varicose (less than 1mm in diameter) and reticular veins (1 to 3mm in diameter). Polidocanol works by damaging the cell lining of blood vessels, causing them to close and eventually be replaced by other types of tissue.
    Pure polidocanol for pharmaceutical use

    Basic Info

    Chemical Name polidocanol
    Synonyms

    nonaoxyethylene monododecyl ether;
    C12E9,Dodecyl nonaethylene glycol ether,Dodecylnonaglycol;
    3,6,9,12,15,18,21,24,27-Nonaoxanonatriacontan-1-ol;
    Polidocanol;
    Dodecylnonaglycol;
    Nonaethyleneglycol monododecyl ether solution;
    2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol;
    Nonaethyleneglycol monododecylether;
    Dodecyl nonaethylene glycol ether;
    dodecylalcohol nonaethoxylate;
    C12E9;

    CAS No. 3055-99-0
    Molecular Formula C30H62O10
    Molecular Weight 582.80700
    PSA 103.30000
    LogP 4.04900

    Properties

    Density 1.007g/cm3
    Boiling Point 615.9ºC at 760mmHg
    Melting Point 33-36ºC
    Flash Point 326.3ºC
    Refractive Index n20/D 1.459
    Storage Condition 2-8ºC

    Safety Info

    Safety Statements S23; S24/25
    HS Code 2909499000

    Synthesis Route

    1-{2-[2-(2-{2-[2-(2-chloro-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-dodecane+triethylene glycol→polidocanol

    Precursor

    1-{2-[2-(2-{2-[2-(2-chloro-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-dodecane
    triethylene glycol

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