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N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

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Origin: China

Cas No: 15421-84-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 15421-84-8 Formula: C10H15N5 Molecular Weight: 205.26000

Description

Trapidil is a vasodilator.

Basic Info

Chemical Name	N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Synonyms	EINECS 239-434-2; (1,2,4)Triazolo(1,5-a)pyrimidin-7-amine,N,N-diethyl-5-methyl; Rocornal; 5-methyl-7-diethylamino-s-triazolo[1,5-a]pyrimidine; AR 12008,Avantrin,N,N-diethyl-5-methyl-[1,2,4]Triazolo[1,5-a]pyrimidin-7-amine; N,N-dimethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine; diethyl-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-amine; Trapidilum [INN-Latin]; Diaethyl-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-amin; Trapymin; 5-Methyl-7-diaethylamino-s-triazolo<1.5-a>pyrimidin; trapidil;
CAS No.	15421-84-8
Molecular Formula	C10H15N5
Molecular Weight	205.26000
PSA	46.32000
LogP	1.27890

Properties

Density	1.21 g/cm3
Refractive Index	1.625

Safety Info

HS Code	2933990090
Signal Word	Warning
Symbol	GHS07
Caution Statement	P261; P305 + P351 + P338
Hazard Declaration	H315; H319; H335

Synthesis Route

5-methyl-(1,2,4)Triazolo(1,5-A)pyrimidin-7(1H)-one→N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
7-Chloro-5-Methyl-[1,2,4]Triazolo[1,5-A]Pyrimidine+Diethylamine→N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	235 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	100 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Subcutaneous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	100 mg/kg	1.Details of toxic effects not reported other than lethal dose value