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N-Trifluoroacetyldoxorubicin

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Origin: China

Cas No: 26295-56-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 26295-56-7 Formula: C29H28F3NO12 Molecular Weight: 639.52700

Description

Doxorubicin metabolite. Cytotoxic interaction with DNA.

Basic Info

Chemical Name	N-Trifluoroacetyldoxorubicin
Synonyms	5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-.α.-L-lyxo-hexopyranosyl]oxy]-, (8S-cis)-;
CAS No.	26295-56-7
Molecular Formula	C29H28F3NO12
Molecular Weight	639.52700
PSA	209.15000
LogP	1.11200

Properties

Density	1.66g/cm3
Boiling Point	855.4ºC at 760 mmHg
Flash Point	471.1ºC
Refractive Index	1.656
Vapor Pressure	3.7E-31mmHg at 25°C

Synthesis Route

S-ETHYL TRIFLUOROTHIOACETATE+ADRIAMYCIN, HYDROCHLORIDE→N-Trifluoroacetyldoxorubicin
ADRIAMYCIN, HYDROCHLORIDE+Trifluoroacetic anhydride→N-Trifluoroacetyldoxorubicin
doxorubicin→N-Trifluoroacetyldoxorubicin

Precursor

S-ETHYL TRIFLUOROTHIOACETATE
Ethyl trifluoroacetate
ADRIAMYCIN, HYDROCHLORIDE
doxorubicin

Downstream Product

Valrubicin

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